Answer: Split into parties of 5 and assign each one a colour, using that colour to identify specific parts of the targets route the team will much more effectively track it down!
Most maps have start locations (there will be a nearby waypoint..) for each colour, if there are not any, use that extremely rare skill you possess: common sense!
Some targets have extremely complicated pathing and may reset (teleport..) partway through their paths - if everyone has completed their assigned routes and not found him, run back and forth until you do!
With a few exceptions, you should always be running in the opposite direction the NPC is! (so go against the little arrows)
Your party needs to assign the following colours!
PINK - GREEN - YELLOW - ORANGE - RED
But Wolf.. why no blue?
2-Mult (Timberline Falls)
Ander “Wildman” Westward (Southsun Cove)
Bookworm Bwikki (Lornar’s pass)
Brekkabek (Harathi Hinterlands)
Crusader Michiele (Sparkfly Fen)
Big Mayana (Sparkfly Fen)
Deputy Brooke (Snowden Drifts)
Devious Teesa (Frostgorge Sound)
Diplomat Tarban (Brisban Wildlands)
Half Baked Komali (Mount Maelstrom)
Poobadoo (Kessex Hills)
Prisoner 1141 (Iron Marches)
Shaman Arderus (Fireheart Rise)
Short-Fuse Felix (Diessa Plateau)
Sotzz the Scallywag (Gendarran Fields)
Tricksy Trekksa (Blazeridge Steppes)
Trillia Midwell (Fields of Ruin)
Yanoka The Rat Wrangler (Fields of Ruin)
Most of these maps were based on the pathing maps posted on Dulfy's website - credit goes to the dedicated players who helped Dulfy organize such valuable information!
Copyright stuffs probably still belongs to Arenanet so dont be trying to sell these or anything..